Job opportunity

Senior Bioinformatics Analyst / Senior Bioinformatics Analystess

ETH Zurich Zürich December 6, 2025

Senior Bioinformatics Analyst

80%-100%, Basel, permanent

The ETH Zurich core facility NEXUS Personalized Health fosters discovery and translational research aimed at enhancing personalized health. Our team, which spans software engineering, biomedical data management, lab automation, and screening services, is committed to applying bioinformatics and statistics for the advancement of biomedical research and clinical applications.

We are currently seeking a Senior Bioinformatics Analyst for the Clinical Bioinformatics Group of NEXUS Personalized Health in Basel, to begin immediately or by mutual agreement.

Job Description

The primary focus of this position is the project-specific analysis of a diverse array of high-throughput multi-omics datasets, including whole-genome and transcriptome sequencing, single-cell, and spatial data. As a Senior Bioinformatics Analyst, you will play a crucial role in designing, executing, and documenting analytical workflows while maintaining scientific rigor and adhering to best practices in your work.

You will lead your assigned analyses while collaborating closely with the group lead and other experts within the NEXUS team. This role combines independent analytical tasks with active participation in joint project planning, interpretation, and dissemination of results.

Your responsibilities will also include the development and maintenance of reproducible analysis pipelines and software tools, supporting the team's shared infrastructure. Additionally, you will ensure that data management aligns with the FAIR principles and assist our partners in implementing best practices for Research Data Management (RDM).

Our projects span biomedical research and clinical diagnostics and cover a broad spectrum of applications—from fundamental NGS data processing to clinical reporting and public health surveillance. NEXUS collaborates closely with academic institutions and hospitals, providing a dynamic environment where scientific excellence and collaboration yield impactful outcomes.

Profile

We are looking for a motivated and detail-oriented colleague who thrives in a collaborative setting and has a strong interest in clinical science and translational research.

  • MSc (or higher) in bioinformatics, computational biology, or a related field
  • At least 3 years of hands-on experience in biomedical, genomics, or integrative research projects involving molecular datasets
  • Proven ability to extract biological insights and visualize complex multi-omics data
  • Demonstrated experience in the analysis of genomics and/or transcriptomics sequencing data
  • Solid programming skills in Python or R
  • Familiarity with HPC environments and Bash scripting
  • Experience with version control systems (e.g., Git)
  • Excellent communication skills in English

Advantageous Qualifications

  • Experience with AI or machine learning methods
  • Background in statistics or software development
  • Familiarity with workflow management systems (e.g., Snakemake, Nextflow)
  • Knowledge of German

Workplace

At NEXUS, we value knowledge exchange and collaborative teamwork, where each member contributes their unique expertise. Being a small group, we maintain flat hierarchies, offer flexible working hours, and promote family-friendly working models. We provide numerous training opportunities and engage in a broad and exciting array of work at the cutting edge of translational research.

We Value Diversity and Sustainability

ETH Zurich is committed to fostering an inclusive culture that promotes equality of opportunity, values diversity, and nurtures a working and learning environment where the dignity and rights of all staff and students are upheld. Sustainability is a core value for us as we strive toward a climate-neutral future.

Curious? So Are We.

We look forward to receiving your online application, including:

  • Cover letter
  • CV
  • Diplomas and certificates
  • References of employment

Apply online using the form below. Only applications matching the job profile will be considered.

For more information about NEXUS, visit our website. Should you have any questions, feel free to contact Dr. Franziska Singer at singer@nexus.ethz.ch (no applications).

About ETH Zurich

ETH Zurich is one of the world's leading universities specializing in science and technology. Renowned for excellent education, cutting-edge fundamental research, and the direct transfer of new knowledge into society, our institution attracts over 30,000 individuals from more than 120 countries. Here, we foster independent thinking and create an environment that inspires excellence. Located in Europe's heart yet connected globally, we work together to devise solutions for the challenges of today and tomorrow.

Work locationZürich, Switzerland

Application Form

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