Senior Bioanalytical Scientist / Senior Bioanalytical Scientistess

Senior Bioanalytical Scientist - Permanent - San Francisco, CA

Lead the science behind tomorrow's medicines by advancing bioanalytical strategies from discovery through clinical development. We are seeking an experienced and highly motivated Senior Bioanalytical Scientist to spearhead the development, optimization, qualification, validation, and execution of bioanalytical assays supporting both discovery and clinical development programs.

Primary Responsibilities

The successful candidate will act as a scientific and technical expert in bioanalytical strategy and assay development. You will work collaboratively with DMPK, In Vivo Pharmacology, Toxicology, Clinical Pharmacology, and other cross-functional teams to generate high-quality bioanalytical data that inform critical drug-development decisions. The ideal candidate will possess strong hands-on expertise with LC-MS/MS or other quantitative bioanalytical technologies and demonstrate the ability to independently drive complex projects.

Skills & Requirements

• MS/PhD in chemistry, analytical chemistry, biochemistry, bioengineering, or related fields with 5+ years of relevant industry or academic experience, or BS with 10+ years of experience
• Strong understanding and experience with the fundamentals of chromatography and analytical separations
• Experience operating and maintaining analytical instrumentation, including HPLC, mass spectrometer, spectrophotometers, and data analysis software

Key Responsibilities

• Perform hands-on laboratory work to support clinical and non-clinical studies, including sample analysis and data interpretation using appropriate bioanalytical technologies and instrumentation
• Operate, troubleshoot, and maintain analytical instruments such as HPLC, mass spectrometer, and other lab equipment
• Review and interpret bioanalytical data, reports, protocols, validation plans, and technical documentation, effectively communicating findings to other departments or external organizations
• Identify trends, anomalies, and potential sources of variability
• Develop, improve, and evaluate new bioanalytical methods and assays to support pharmaceutical development programs
• Troubleshoot complex assay and sample-analysis issues, developing scientifically sound solutions
• Partner with DMPK, Biology, Toxicology, and Clinical Pharmacology scientists to support PK, toxicokinetic, exposure-response, and biomarker analyses, and communicate results to cross-functional project teams
• Contribute to departmental strategy, technology development, and process improvement initiatives by staying current with advances in bioanalytical technologies, regulatory guidance, and industry practices
• Contribute to regulatory submissions
• Author and/or review bioanalytical method development reports, validation reports, study reports, protocols, SOPs, and technical reports
• Manage external CROs and testing laboratories, including method transfer, assay execution, data review, and issue resolution

Compensation

$120,000 - $150,000 Per Annum

If you are interested in this exciting opportunity, please Apply online using the form below. Only applications matching the job profile will be considered.

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