Novartis Pharma AG - March 16, 2026

Job ID

REQ-10071301

Date: Feb 11, 2026

Location: Basel, Switzerland

Full time, onsite

#LI-Onsite

Summary

At Novartis, we are reimagining medicine to improve and extend people's lives. By leveraging innovative science and technology, we strive to address some of society's most challenging healthcare issues. Our mission involves discovering and developing breakthrough treatments and finding new ways to deliver them to as many patients as possible. We believe that the answers lie in empowering curious, courageous, and collaborative individuals to ask bold questions and make informed decisions.

Located in Basel, Switzerland, the Biomedical Research division is at the heart of Novartis' mission, focusing on designing and developing new molecules for patient treatment. We are seeking a highly motivated, passionate researcher with a robust background in chemistry or related life sciences and a curious mindset to join us in inventing innovative medicines and advancing drug discovery.

About the Role

The Biomedical Research RNAi Initiative is on the lookout for a passionate and creative scientist to join our RNA synthesis team. You will work collaboratively in a multidisciplinary environment, navigating the interface between research and development to discover and develop novel siRNA therapies aimed at addressing high unmet medical needs.

Your Responsibilities

Plan and execute small scale oligonucleotide syntheses using array-based, automated synthetic technologies.
Conduct experiments in a state-of-the-art laboratory and provide novel siRNAs to advance therapeutic siRNA projects.
Collaborate with the project team to integrate experimental data, develop scientific hypotheses, and prioritize novel oligonucleotide chemistries to tackle key project questions.
Support and coach team members by sharing your expertise and experiences across the work environment.
Present and discuss scientific results during internal meetings and research boards.
Ensure high levels of laboratory safety and maintain infrastructure standards.

What You Will Bring to the Role

A Master’s degree with a minimum of 3 years of industry experience in a Pharma Lab, focusing on synthetic organic chemistry. PhD graduates within 6 months of their defense may be considered.
Practical knowledge in small scale oligonucleotide synthesis is essential.
Knowledge of conjugation to linkers, modifiers, and payloads is a plus.
A genuine passion for automated oligonucleotide chemistry experimentation.
Ability to critically interpret results, formulate new experimental hypotheses, and make calculated decisions.
Interest in disruptive technologies and science trends, such as new drug modalities and automation, and their relevance in drug discovery and development.
A mindset embracing curiosity, creativity, collaboration, and an openness to diverse perspectives.
An organized work style with attention to detail, flexibility, and a commitment to high-quality outputs.
Capability to work within a fast-paced, team-oriented matrix environment.
Excellent oral and written communication skills.

Additional Information

Only applications matching the job profile will be considered.

Apply online using the form below.

Accessibility and Accommodation

Novartis is committed to providing reasonable accommodation to all individuals. If you require accommodation due to a medical condition or disability during the recruitment process or need more information regarding the essential functions of this position, please reach out via email to inclusion.switzerland@novartis.com. Include the nature of your request and your contact information, along with the job requisition number in your message.

Why Novartis

Supporting people with diseases and their families requires more than innovative science; it necessitates a community of talented, passionate individuals who collaborate, inspire, and uplift one another. Together, we can achieve breakthroughs that transform patients' lives. Are you ready to create a brighter future with us?

Learn more about our people and culture here.

Benefits and Rewards

Discover the ways we will support your personal and professional growth.

Read our handbook (PDF 30 MB).

Senior Scientist / Senior Scientistess - Small Scale Oligonucleotide Synthesis