Job ID: REQ-10051302
Date: Jun 03, 2025
Location: Switzerland
Summary
Join our Diseases of Ageing and Regenerative Medicine (DARe) department at Biomedical Research as a Senior Principal Scientist. In this role, you will spearhead in-vivo imaging initiatives, pioneering innovative imaging techniques and technologies to advance Drug Discovery across key research areas, including Oncology, Immunology, Neuroscience, and Cardiovascular and Metabolic diseases.
About the Role
The successful candidate will lead the in-vivo imaging facility to enhance the drug discovery process through advanced imaging techniques, such as magnetic resonance imaging, ultrasound, computerized tomography, and optical imaging. You will assess pharmacological interventions in relevant small rodent disease models and identify and characterize imaging biomarkers.
Key Responsibilities
- Provide leadership for the in-vivo imaging facility, including line management of laboratory associates and coordination of activities and technical development.
- Maintain equipment infrastructure while leading the enhancement of techniques to address biological questions related to the projects, including MRI, ultrasound, micro-CT, and optical imaging.
- Develop and program imaging and spectroscopy protocols relevant to preclinical pharmacological studies.
- Interpret, analyze, and report data derived from these techniques, presenting results effectively in both written and oral formats at team meetings and to management decision boards.
- Design, execute, analyze, and report state-of-the-art in-vivo animal experiments involving imaging/spectroscopy.
- Integrate in-vivo imaging results with ex-vivo tissue and biofluid analyses.
- Collaborate with project team members across the organization and animal facilities to ensure timely execution of complex in vivo studies.
- Support the characterization of translational imaging biomarker candidates in collaboration with the clinical imaging group at Novartis.
Minimum Requirements - What You Will Bring to the Role
- A scientific background in a relevant discipline (Physics, Chemistry, Engineering, or Life Science) with a PhD and Postdoctoral research, along with 2-3 years of industry experience or equivalent academic experience, including extensive in-vivo experimentation and imaging research.
- Relevant experience in in-vivo imaging of small rodents documented through publications.
- Laboratory experience in in-vivo MR techniques, providing both technical expertise and a biological background to guide in-vivo experimentation.
- Prior management experience leading an in-vivo imaging laboratory in either an academic or industrial setting.
- A motivation to deepen your understanding of diseases of aging and regenerative medicine.
- A proactive attitude coupled with an inquisitive mindset and a proven ability to formulate, articulate, and critically evaluate scientific experiments.
- Excellent teamwork skills and an aptitude for collaborating within cross-disciplinary teams.
- High adaptability to learning new techniques and a commitment to staying updated on the latest developments in animal research.
- Fluency in written and oral English, complemented by exceptional presentation skills.
Technical Skills
- Experience with in-vivo anatomical (MRI, CT, ultrasound) and molecular imaging techniques (e.g., PET, optical) as well as in-vivo spectroscopy (e.g., 31P MRS).
- Programming skills in the Bruker environment and image analysis (e.g., Matlab).
- Proficiency in data analysis, hypothesis testing, and problem-solving.
- Accreditation for animal experimentation (LTK1/LTK2, FELASA B, or equivalent).
Accessibility and Accommodation
Novartis is dedicated to building an inclusive work environment. If you require reasonable accommodations during the recruitment process due to a medical condition or disability, please contact us via email at inclusion.switzerland@novartis.com. Include the job requisition number in your message for reference.
Why Novartis
At Novartis, we believe that helping individuals with diseases, along with their families, requires more than just innovative science. We thrive as a community of passionate individuals who collaborate, support, and inspire one another to achieve breakthroughs that transform lives. Are you ready to join us in creating a brighter future together?
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Benefits and Rewards
Explore our benefits handbook to discover the various ways we support your personal and professional growth: Novartis Benefits and Rewards.
Application Process
Apply online using the form below. Please note that only applications matching the job profile will be considered.
Company Information
Division: Biomedical Research
Business Unit: Pharma Research
Location: Basel City, Switzerland
Company / Legal Entity: Novartis Pharma AG (C028)
Functional Area: Research & Development
Job Type: Full time
Employment Type: Regular
Shift Work: No
Novartis is committed to building an outstanding, inclusive work environment with diverse teams representing the patients and communities we serve.