Senior Principal Scientist - Proteomics / Senior Principal Scientistess - Proteomics

Job ID

REQ-10081747

Date: Jul 09, 2026

Location: Switzerland

Available in: English

Summary

We are seeking an enthusiastic, curious, and highly motivated proteomics expert to join our Discovery Sciences Translational Profiling (TP) team in Basel. TP is a global group of professionals specializing in proteomics, metabolomics, lipidomics, super-resolution microscopy, and data science within Novartis Biomedical Research, located in Basel, Switzerland, and Cambridge, US.

As a Senior Principal Scientist, you will lead a proteomics lab team, play a vital role in advancing cutting-edge technologies, and contribute to our global proteomics strategy. This position involves collaboration with scientists and project teams across five disease areas within Novartis Biomedical Research, all dedicated to developing transformative therapeutics for patients worldwide.

About the Role

Internal Job Title: Senior Principal Scientist

Position Location: Basel, CH onsite #LI-onsite

Note: This role is based in Basel, Switzerland. Novartis is unable to offer relocation support for this role; please only apply if this location is accessible to you.

Key Responsibilities

• Lead and oversee high-impact proteomics analyses across drug discovery programs, from early research to translational studies involving patient samples.
• Contribute to interdisciplinary research programs within a collaborative, matrixed environment, partnering with internal cross-functional teams and external collaborators.
• Maintain a state-of-the-art proteomics platform by staying updated on technological advancements and aligning capabilities with internal project needs and application priorities.
• Drive innovation in biomedical research by championing advanced technologies and cross-disciplinary initiatives, enabling novel applications of proteomics, such as low-input and spatial proteomics.
• Coach and mentor junior scientists, support project teams, and facilitate the work of direct/matrix reports and key collaborators.

Essential Requirements

• PhD in biology, biochemistry, or a related discipline, with at least five years of academic experience in proteomics applied to biomedical research, or comparable experience in the biotechnology/pharmaceutical industry.
• Extensive knowledge of and experience with proteomics approaches and technologies, demonstrated by a strong publication record and significant contributions to the proteomics field.
• Strong data science skills with a solid understanding of biostatistical principles.
• Proven ability to lead a cross-functional team in a matrix environment.
• Collaborative, innovative mindset with the ability to quickly adapt to a dynamic, fast-paced, multi-disciplinary research atmosphere.
• Exceptional communication and presentation skills for multidisciplinary audiences across various seniority and expertise levels.

Desirable Requirements

• Experience with pathway analysis and multi-omics data integration, along with knowledge of advanced data science approaches, including skills in Python and/or R.
• Expertise in spatial and low input proteomics.

Benefits & Rewards

At Novartis, we are committed to reimagining medicine together and rewarding the talented individuals who make it possible.

Expected Annual Base Salary Range for this role: CHF 126,000 - CHF 234,000

The base salary offered will be determined based on gender-neutral objectives such as relevant skills, competencies, and experience, in accordance with the Novartis pay setting policy.

The rewards of being part of our team extend beyond base pay and incentives. We offer a range of competitive benefits designed to help you thrive both personally and professionally, including insurance plans, retirement plans, well-being resources, and global recognition programs. Additionally, we provide flexible and hybrid working options, where possible, and a minimum of 14 weeks paid parental leave.

In addition to your base salary, you may be eligible for a performance-based bonus depending on certain performance parameters. Long-term equity awards granted at the group level may also be part of your compensation package. Further details will be provided during the application process.

Read our brochure to discover more about our global total rewards offerings: Novartis Life Handbook

Commitment to Diversity and Inclusion

Novartis is dedicated to fostering an outstanding, inclusive work environment and diverse teams that reflect the patients and communities we serve.

Accessibility and Accommodation

Novartis is committed to working with and providing reasonable accommodations to all individuals. If you require accommodation due to a medical condition or disability during the recruitment process or would like more detailed information about the essential functions of this position, please reach out to us.

Why Novartis

Helping people with diseases and their families requires more than innovative science; it demands a community of passionate individuals like you who collaborate, support, and inspire one another. Together, we can achieve breakthroughs that change patients' lives. Ready to create a brighter future together?

Learn more about Novartis.

Application Process

Apply online using the form below. Only applications matching the job profile will be considered.