Job ID
REQ-10076082
Apr 20, 2026
Switzerland
Summary
Location: Basel, Switzerland #onsite
Role purpose: The position is within the Global Technical R&D department of Global Drug Development. Within this organization, Chemical & Analytical Development (CHAD) plays an essential role in the development of processes for the manufacturing and analysis of Antibody-Oligonucleotide conjugates (AOCs).
About the Role
Your Responsibilities:
- Utilize your strong expertise and creativity in chemical synthesis and process development to lead the setup of future chemistry and manufacturing pathways for Antibody-Oligonucleotide Conjugates (AOCs) and other complex constructs.
- Act as a key contributor to engage and ensure adequate support and knowledge transfer for Novartis BD&L activities focusing on bioconjugation chemistry and manufacturing processes.
- Conduct experimental designs in our laboratories, enabling you to interpret and report data and results.
- Coordinate and ensure the timely availability and transfer of manufacturing instructions to the pilot plant within Chemical & Analytical Development (CHAD) or CMOs.
- Collaborate closely as a core member of cross-functional teams with our internal and external partners to ensure timely and quality delivery of new nucleotide drugs to our patients.
- Provide relevant process documentation in support of filing of dossiers.
- Participate actively in scientific exchange groups within Novartis and Academia, maintaining excellent collaboration with our customers.
Minimum Requirements
Education:
We are looking for candidates with a PhD and PostDoc in organic chemistry, preferably with a specialization in the field of bio-conjugation or chemical modification of fermentation products.
Experience and Expertise:
- Recent and proven knowledge in the area of chemical bioconjugation or chemical modification of fermentation products, such as Antibody-Drug Conjugates, or other complex molecular structures, is essential.
- A strong requirement of 2-5 years of experience in synthesis/chemical process development, with piloting experience under GMP being a benefit.
- An independent and self-motivated work style with team orientation and effective communication is essential.
- Advanced knowledge of software and computer tools, such as the Office package and DoE tools, is desirable.
Language Skills
- Proficiency in the English language (oral and written) is required, while knowledge of German and other languages is beneficial.
Commitment to Diversity and Inclusion
Novartis is dedicated to fostering an outstanding, inclusive work environment and creating diverse teams that are representative of the patients and communities we serve.
Accessibility and Accommodation
Novartis is committed to working with and providing reasonable accommodation to all individuals. If you need a reasonable accommodation for any part of the recruitment process, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Why Novartis
Helping people with disease and their families takes more than innovative science. It requires a community of smart, passionate individuals. Collaborating, supporting, and inspiring one another, we combine efforts to achieve breakthroughs that change patients' lives. Ready to create a brighter future together? Learn more here.
Benefits and Rewards
Discover all the ways we’ll help you thrive personally and professionally. Read our handbook.
Division
Development
Business Unit
Development
Location
Switzerland
Site
Basel (City)
Company / Legal Entity
C028 (FCRS = CH028) Novartis Pharma AG
Functional Area
Research & Development
Job Type
Full time
Employment Type
Regular
Shift Work
No
Senior Expert Science & Technology - PRD Chemist
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