Senior Bioinformatics Analyst / Senior Bioinformatics Analystess

ETH Zurich - December 12, 2025

Senior Bioinformatics Analyst

80%-100%, Basel, permanent

The ETH Zurich core facility NEXUS Personalized Health enables discovery and translational research for personalized health. We offer a broad range of expertise, from software engineering and biomedical data management to lab automation and screening services. Embedded in this multi-disciplinary team, the clinical bioinformatics group applies its expertise in bioinformatics and statistics to advance biomedical research and clinical applications.

We are recruiting a Senior Bioinformatics Analyst for the Clinical Bioinformatics Group of NEXUS Personalized Health in Basel, with a start date of immediate effect or by mutual agreement.

Job Description

The primary focus of this position is the project-specific analyses of diverse high-throughput multi-omics datasets, encompassing a wide range of data types such as whole-genome and transcriptome sequencing, single-cell, and spatial data. As a Senior Bioinformatics Analyst, you will play a key role in designing, executing, and documenting analytical workflows, applying scientific rigor and best practices throughout your work.

While taking the lead on your assigned analyses, you will work closely with the group lead and other experts within the NEXUS team. This role combines independent analytical work with active participation in joint project planning, interpretation, and dissemination of results.

Your responsibilities will also include:

  • Development and maintenance of reproducible analysis pipelines and software tools, contributing to the team's shared infrastructure.
  • Ensuring that data is managed in accordance with the FAIR principles.
  • Supporting partners in adopting best practices for Research Data Management (RDM).

Our projects span biomedical research and clinical diagnostics, covering a wide range of applications—from basic NGS data processing to clinical reporting and public health surveillance. NEXUS collaborates closely with academic institutions and hospitals, offering a dynamic environment where scientific excellence and collaboration drive impactful outcomes.

Profile

We are looking for a motivated and diligent colleague who enjoys working in a collaborative environment and has a strong interest in clinical science and translational research.

  • MSc (or higher) in bioinformatics, computational biology, or a related field
  • At least 3 years of hands-on experience in biomedical, genomics, or integrative research projects involving molecular datasets
  • Proven ability to extract biological insights and visualize complex multi-omics data
  • Demonstrated experience in the analysis of genomics and/or transcriptomics sequencing data
  • Solid programming skills in Python or R
  • Familiarity with HPC environments and Bash scripting
  • Experience with version control systems (e.g., Git)
  • Excellent communication skills in English

Advantageous are:

  • Experience with AI or machine learning methods
  • Background in statistics or software development
  • Familiarity with workflow management systems (e.g., Snakemake, Nextflow)
  • Knowledge of German

Workplace

At NEXUS, we value knowledge exchange and teamwork, where each member contributes their expertise. As a small group, we maintain flat hierarchies and offer flexible working hours along with family-friendly working models. We provide training opportunities within a broad and exciting field of work at the cutting edge of translational research.

We Value Diversity and Sustainability

In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity, and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Sustainability is a core value for us—we are consistently working towards a climate-neutral future.

Curious? So are we.

We look forward to receiving your online application using the form below.

Note: Only applications matching the job profile will be considered.

Further information about NEXUS can be found on our website. For any inquiries, please contact Dr. Franziska Singer (email: singer@nexus.ethz.ch, no applications).

About ETH Zurich

ETH Zurich is one of the world’s leading universities specializing in science and technology. Renowned for our excellent education, cutting-edge research, and direct transfer of new knowledge into society, we host over 30,000 people from more than 120 countries in an environment that promotes independent thinking and inspires excellence. Located in the heart of Europe, we forge connections worldwide to develop solutions for today’s and tomorrow’s global challenges.

Location : Zürich
Country : Switzerland

Application Form

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