Scientific Assistant to Engineer for Next-Generation Neural Interfaces / Scientific Assistantess to Engineer for Next-Generation Neural Interfaces

Scientific Assistant to Engineer Next-Generation Neural Interfaces

100%, Zurich, fixed-term

The brain is an intricate system composed of billions of neurons that interact to facilitate cognitive functions. Capturing this network activity at a single-cell level across multiple brain areas is vital for understanding its complexities. Current methods for interfacing with the brain often fall short in terms of temporal resolution, biocompatibility, or access to deeper brain regions. To address these limitations, we have developed Ultra-Flexible Tentacle Electrodes (UFTEs), which are fibers significantly smaller than a human hair (2.4 µm x 7 µm cross-sectional area). These electrodes have enabled us to record single-unit activity from various brain regions in freely moving rodents, demonstrating stability over nearly a year. Unlike traditional stiff electrodes, UFTEs evade recognition by the brain's immune system and offer a superior signal-to-noise ratio compared to existing flexible electrodes (Yasar & Gombkoto et al., Nature Communications, 2024).

Project Background

Our in vivo validations of UFTEs have shown promising results, but additional steps are needed to facilitate broader adoption as an advanced research tool within the neuroscience community. With a project grant from Innosuisse, we aim to enhance the user-friendliness and scalability of UFTEs, integrate multimodal recording and stimulation capabilities, and adapt these technologies for use in non-human primate studies. Our ultimate goal is to bring UFTEs to market as a state-of-the-art research tool.

Job Description

• Developing a new MEMS-based scalable assembly and insertion system for our Ultra-Flexible Tentacle Electrodes and supporting its in vivo validation.
• Establishing protocols for characterizing UFTEs and enhancing their long-term stability.
• Designing and executing regular cleanroom microfabrication of UFTEs.

This is a 1.5-year position that can start in April 2026 (exact date by agreement). Follow-up positions may be available depending on interest and funding.

Profile

• Swiss citizen/permanent resident or EU/EFTA national.
• Master's degree in Mechanical Engineering, Microsystems Engineering, Materials Science, Physics, Biomedical Engineering, or a related field.
• Required skills: Micro- or nanofabrication and characterization in a cleanroom environment, 2D and 3D design (AutoCAD, SolidWorks, etc.), prototyping, basic electronics and circuit design skills, and assembly/manipulation of microscopic components.
• Ability to work independently and drive projects to successful completion while establishing new fabrication/testing protocols based on literature reviews.
• Excellent problem-solving capabilities.
• Strong communication skills, both verbal and written, coupled with the ability to work effectively within a team.
• (Optional) Previous experience at FIRST Lab (ETH Zurich) and continued access to that facility would be a significant advantage.

Workplace

The position is based at ETH Zurich, a premier institution fostering cutting-edge research and interdisciplinary collaboration.

We Offer

• An opportunity to engage in the burgeoning fields of neural interfaces and neuroscience within a highly interdisciplinary environment at a world-renowned university.
• Involvement in bringing neural implant technology to market readiness for commercialization.
• Experience of the *full lifecycle*, from design and build to *in vivo* brain-machine interface applications.
• Access to a robust network of neuroscientists and engineers at the Institute of Neuroinformatics, Neuroscience Center Zurich (ZNZ), and worldwide collaborative labs.
• Flexible working hours and locations; while the majority of your time will be spent between the lab and cleanroom, we also support remote work for design tasks.

We Value Diversity and Sustainability

In line with our core values, ETH Zurich promotes an inclusive culture. We are committed to equality of opportunity, value diversity, and cultivate a work environment that respects the rights and dignity of all staff and students. For additional information on our commitment to fair practices, visit our Equal Opportunities and Diversity website. We also prioritize sustainability and are actively working on initiatives towards a climate-neutral future.

Curious? So Are We.

Apply online using the form below. Only applications matching the job profile will be considered.

About ETH Zurich

ETH Zurich is a world-leading university specializing in science and technology. Renowned for our exceptional education and pioneering research, we aim to transfer new knowledge directly to society. With over 30,000 individuals from more than 120 countries, ETH Zurich fosters an environment promoting independent thinking and excellence. Situated in the heart of Europe, we collaborate globally to generate solutions for contemporary challenges.