Research Associate for in vivo Nonmalignant Hematology Research
Roche Switzerland bridges the gap between pharmaceuticals and diagnostics, with key research and development functions located here. We are currently seeking a dedicated and skilled professional to join our long-term client, F. Hoffmann-La Roche AG in Basel.
Background
We are looking for a Research Associate to assess the efficacy, safety, and translatability of gene therapies in nonmalignant hematology, including bleeding and thrombotic disorders, anemia, and more. In collaboration with a larger team, you will work with preclinical animal models and human patient material (blood and plasma) to characterize various gene therapy assets related to hemostasis and thrombosis. The role involves hands-on experience in end-to-end experiments, from conducting animal studies to sample collection and various ex vivo assays.
Tasks & Responsibilities
- Design, execute, and analyze diverse in vivo experiments, including intravenous injections, blood and plasma collection, and bleeding and thrombosis models.
- Characterize the efficacy and safety of new gene therapy assets using molecular and biochemical assays (e.g., ELISA, thrombin generation assay, chromogenic assays) in murine and human samples.
- Prepare, handle, and test patient-derived material (blood and plasma) in in vitro and ex vivo settings.
- Perform data analysis and present results within the team.
- Maintain thorough documentation and contribute to lab organization, safety, and inventory management.
Must Haves
- MSc or BSc in Life Sciences (e.g., molecular biology, pharmacology, immunology, coagulation) with at least 2-3 years of hands-on animal study experience (No PhD accepted).
- Alternatively, completed an apprenticeship as a Research Associate ("Lehrabschluss") with at least 4-5 years of academic or industry experience.
- Active LTK1 (FELASA or equivalent) certification.
- Demonstrated hands-on experience with rodent work, including intravenous injections and blood collection.
- Strong experience in experimental design and data analysis.
- Ability to independently execute and manage in vivo studies from start to finish.
- Fluency in English.
Additional Qualifications
- Experience with animal surgery.
- Knowledge or experience in coagulation and/or gene therapy.
- Hands-on experience with molecular and biochemical assays (e.g., ELISA, thrombin generation, chromogenic assays).
- Prior industry experience.
What You Will Be Offered
- An opportunity to work in one of the world's leading pharmaceutical companies.
- A modern campus with ample green spaces and meeting areas.
- Central location in Basel.
- Remote work options available.
- A diverse job profile.
- Further training opportunities through temptraining.
- Collaboration within a dynamic and motivated team.
If you are interested, please apply online using the form below. Only applications matching the job profile will be considered.