Principal Scientist - Radiochemistry / Principal Scientistess - Radiochemistry

Job ID

REQ-10052675

Date: May 27, 2025

Location: Basel, Switzerland

Type: Full time, onsite, #LI-onsite

Summary

Novartis is seeking a Principal Scientist, Radiochemist in Basel, Switzerland, to join the Global Discovery Chemistry team. This role focuses on developing novel radioligand therapies for oncology, requiring a strong background in radiochemistry and collaboration within a dynamic team.

Join us and help us discover breakthrough therapies for millions of patients worldwide!

Key Responsibilities

• Collaborate in multidisciplinary teams to develop radioligand therapies.
• Conduct research in radiochemistry and perform quality control of radioligands.
• Mentor team members and contribute to scientific publications and patents.

About the Role

The role:

At Novartis, we are reimagining medicine to improve and extend people's lives. We employ innovative science and technology to address some of society's most challenging healthcare issues. Our focus is on discovering and developing breakthrough treatments and identifying new ways to deliver them to a broader audience. We believe that the answers are found when curious, courageous, and collaborative individuals are empowered to ask new questions, make bold decisions, and take calculated risks.

In Global Discovery Chemistry (GDC) in Basel, Switzerland, we sit at the core of Novartis' purpose. We are looking for a highly motivated and passionate researcher with a strong scientific background in radiochemistry and a curious mindset. Cultural agility to work within a highly dynamic team to identify new targeting vectors for radioligand therapies (RLT) is essential. Join us and help reimagine medicine!

Responsibilities

• Work collaboratively within a multidisciplinary project team to discover and develop novel radioligand therapies in oncology.
• Conduct cutting-edge research in radiochemistry and radionuclide therapies.
• Develop and validate radiosynthesis protocols for new Ga-68 diagnostic and Lu-177 therapeutic radiopharmaceuticals.
• Lead the proposal, evaluation, interpretation, and validation of new radiolabelling procedures with radiometals.
• Perform quality control of radioligands using HPLC, TLC, and SEC in a radiochemistry lab environment.
• Collaborate with internal and external partners to advance project goals.
• Ensure compliance with radiation safety regulations.
• Mentor, coach, and develop a dynamic team of scientific associates.
• Present scientific results at project/group meetings, decision boards, and external conferences.
• Contribute to patent inventorship and scientific publications.
• Participate in global initiatives shaping the future of drug discovery.

Minimum Requirements

• A PhD in chemistry or a related life science discipline with specialized knowledge in radiochemistry.
• Extensive hands-on experience in radiochemistry, including metal labelling of peptides and proteins.
• A proven track record in initiating or significantly contributing to cutting-edge research.
• A mindset characterized by curiosity, creativity, collaboration, and a desire for self-development.
• Interest in disruptive technologies and their applications to drug discovery.
• Ability to work effectively in a fast-paced, team-oriented environment.
• Excellent oral and written communication skills, along with strong influencing abilities.

Application Process

To apply, use the form below. Please note, only applications matching the job profile will be considered.

Accessibility and Accommodation

Novartis is committed to working with and providing reasonable accommodation to all individuals. If you need reasonable accommodation for any part of the recruitment process, please send an email to Show e-mailm">Show e-mail with your request and contact information.

Why Novartis

Helping people with disease and their families takes a community of smart, passionate people like you. By collaborating and inspiring each other, we achieve breakthroughs that change patients' lives. Ready to create a brighter future together? Learn more here.

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Benefits and Rewards

Read our handbook to learn about all the ways we'll help you thrive personally and professionally: Discover our Benefits.

Division

Biomedical Research

Business Unit

Pharma Research

Location

Switzerland

Site

Basel (City)

Company / Legal Entity

C028 (FCRS = CH028) Novartis Pharma AG

Functional Area

Research & Development

Job Type

Full time

Employment Type

Regular

Shift Work

No

Novartis is committed to building an outstanding, inclusive work environment with diverse teams representative of the patients and communities we serve.