Principal Scientist / Principal Scientistess

Job ID

REQ-10075990

April 17, 2026

Location: Basel - Onsite

Summary

The Oncology Translational Research (OTR) group within Novartis Biomedical Research is seeking a highly motivated lab head to drive the translational strategy for early clinical radioligand therapy (RLT) programs. This role will involve collaborative efforts with various groups across the drug development spectrum, including drug discovery, data science, and early clinical development. The successful candidate will lead a team and be responsible for designing and executing preclinical translational studies and clinical biomarker plans.

About the Role

The OTR group is poised for exciting growth, and we invite you to become a critical part of our mission.

Key Responsibilities:

• Lead a research team and collaborate with groups across BR Oncology.
• Contribute to biomarker strategies and supervise translational experimental plans for various RLT drug discovery programs.
• Design and conduct translational studies, dissect biological mechanisms driving response and resistance to RLT, and develop rational drug combinations.
• Mentor and develop associates with varying levels of experience.

Essential Requirements:

• Ph.D. in molecular, cellular, cancer biology, or related fields.
• A minimum of 2 years of Postdoctoral and/or industry experience in an oncology/cancer biology relevant field.
• A recognized academic publication record.
• A deep understanding of cancer cell biology and familiarity with innovative cell and molecular biology techniques.
• Excellent creative thinking and problem-solving skills paired with scientific curiosity.
• Proficiency in collaborative and flexible work on various projects.
• Strong communication skills with an aptitude for conveying complex scientific concepts.

Desirable Requirements:

• Strong foundational knowledge and experience in cell death mechanisms, DNA damage response and repair, radiobiology, or RLT.
• Proficiency with data mining and computational skills.
• Proven track record in managing a research team and scientific projects.

Accessibility and Accommodation

Novartis is dedicated to creating an inclusive environment and providing reasonable accommodation to individuals as needed. If you require assistance due to a medical condition or disability at any point during the recruitment process, please reach out to us at diversity.inclusion_ch@novartis.com, specifying your request and your contact information. Please include the job requisition number in your message.

Why Novartis

At Novartis, we believe that helping individuals with diseases and their families requires more than innovative science. It takes a community of dedicated and passionate individuals, collaborating, supporting, and inspiring each other to achieve breakthroughs that change patients' lives. Join us in creating a brighter future together. Learn more here.

Benefits and Rewards

Discover all the ways we support your personal and professional growth. Read our handbook here.

Job Details

• Division: Biomedical Research
• Business Unit: Research
• Location: Switzerland
• Site: Basel (City)
• Company / Legal Entity: C028 (FCRS = CH028) Novartis Pharma AG
• Functional Area: Research & Development
• Job Type: Full time
• Employment Type: Regular
• Shift Work: No

Principal Scientist - Oncology Translational Research

Apply online using the form below. Please note that only applications matching the job profile will be considered.