Job ID
REQ-10066548
Location
Basel, Switzerland
Summary
We are seeking a highly motivated and experienced PhD-level scientist to lead our mid/large xRNA synthesis team in Basel. This position requires extensive collaboration within a multidisciplinary environment, bridging research and development to discover and advance innovative siRNA therapies that address significant unmet medical needs.
About the Role
Key Responsibilities
- Oversee a state-of-the-art oligonucleotide synthesis facility, efficiently managing both capital and consumables budgets.
- Lead and guide a team of scientists specializing in oligonucleotide synthesis and purification at millimole scale to support our growing siRNA portfolio.
- Ensure the delivery of high-quality siRNA products for both in vitro screening and in vivo evaluation within drug candidate pipelines.
- Collaborate with existing xRNA oligonucleotide synthesis teams in Basel and Cambridge.
- Provide technical leadership to the scale-up team in oligonucleotide synthesis, optimizing methodologies and processes to improve efficiencies.
- Work alongside synthetic chemists and project teams to scale up new siRNA chemistries that address critical scientific challenges, facilitating their seamless transition into development.
- Document and effectively communicate results and scientific insights to internal and external stakeholders through patent applications and scientific publications.
- Mentor and support team members by sharing technical expertise and hands-on experience within the work environment.
- Exhibit excellent problem-solving skills and a solution-oriented mindset.
Qualifications and Requirements
- A PhD in synthetic chemistry focused on oligonucleotides, with 2-3 years of industry experience.
- Proven practical experience in oligonucleotide solid-phase synthesis and downstream processing, with expertise in mid/large scale oligo synthesis and process development.
- Demonstrated leadership abilities and experience in developing scientific teams.
- Capacity to promote and implement innovative ideas within a global team context.
- Strong independent problem-solving skills.
- Proven collaborative attitude.
- Proficiency in managing multiple priorities effectively while maintaining necessary focus.
- Excellent verbal and written communication abilities.
Commitment to Diversity and Inclusion
Novartis is committed to building an outstanding, inclusive work environment and diverse teams that are representative of the patients and communities we serve.
Accessibility and Accommodation
Novartis is committed to working with and providing reasonable accommodation to all individuals. If you require reasonable accommodation for any part of the recruitment process or need more detailed information about the essential functions of a position, please reach out via email at inclusion.switzerland@novartis.com. Be sure to include your request's nature and your contact information, as well as the job requisition number.
Why Novartis
Helping people with disease and their families takes more than innovative science; it takes a community of smart, passionate individuals like you. By collaborating and inspiring each other, we can achieve breakthroughs that change patients' lives. Ready to create a brighter future together? Learn more.
Benefits and Rewards
Discover all the ways we can help you thrive personally and professionally by reading our handbook: View handbook.
Application Process
To apply for this position, please apply online using the form below. Only applications matching the job profile will be considered.
Division
Biomedical Research
Business Unit
Research
Location
Switzerland
Site
Basel (City)
Company / Legal Entity
C028 (FCRS = CH028) Novartis Pharma AG
Functional Area
Research & Development
Job Type
Full time
Employment Type
Regular
Shift Work
No
Work locationBASEL, Switzerland