Novartis is seeking a Principal Scientist, Radiochemist to join the Global Discovery Chemistry team in Basel, Switzerland. This role is focused on developing novel radioligand therapies for oncology and requires a strong background in radiochemistry along with collaboration within a dynamic team.
Join us in discovering breakthrough therapies for millions of patients worldwide!
Key Responsibilities
Collaborate in multidisciplinary teams to develop radioligand therapies.
Conduct research in radiochemistry and perform quality control of radioligands.
Mentor team members and contribute to scientific publications and patents.
About the Role
At Novartis, we are reimagining medicine to improve and extend people's lives. We leverage innovative science and technology to tackle some of society's most pressing healthcare challenges, discovering and developing breakthrough treatments along the way. Our commitment to empowering curious, courageous, and collaborative thinkers allows us to continuously advance our science to help patients in need.
In the Global Discovery Chemistry (GDC) team in Basel, Switzerland, we’re at the core of Novartis's mission. We are looking for a highly motivated researcher with a strong scientific background in radiochemistry and a curious mindset. Cultural agility in working within a dynamic team is essential as we aim to identify new targeting vectors for radioligand therapies (RLT). Become a part of our mission to reimagine medicine!
Your Responsibilities
Your responsibilities will include, but are not limited to:
Working collaboratively in a multidisciplinary project team to uncover and develop novel radioligand therapies in oncology.
Conducting cutting-edge research in radiochemistry and radionuclide therapies, including the development and validation of radiosynthesis protocols for new Ga-68 diagnostic and Lu-177 therapeutic radiopharmaceuticals.
Taking a lead role in proposing, evaluating, interpreting, and validating novel radiolabelling procedures with radiometals along with automation and advanced formulation development.
Performing quality control of radioligands using High Performance Liquid Chromatography (HPLC), Thin Layer Chromatography (TLC), and Size Exclusion Chromatography (SEC). Release radioligands for in vitro and in vivo preclinical studies.
Deploying novel technologies and collaborating with internal and external partners to advance projects.
Ensuring adherence to radiation safety regulations, including training, dosimetry, and the release and disposal of radioactive waste.
Mentoring, coaching, and developing a dynamic team of scientific associates.
Communicating and presenting scientific results at project and group meetings, decision boards, and external conferences.
Contributing to patent inventorship and scientific publications.
Participating in global initiatives that shape the future of drug discovery at Biomedical Research beyond pipeline projects.
Minimum Requirements
The ideal candidate will bring the following qualifications and skills:
A strong passion for hands-on chemistry experimentation in the laboratory with the ability to critically interpret results, develop new experimental hypotheses, and make informed decisions.
A PhD in chemistry or a related life science discipline with specialized knowledge in radiochemistry acquired through postdoctoral and/or industry experience.
Extensive hands-on experience in radiochemistry, including metal labelling (e.g., Ga-68, Lu-177) of peptides and proteins. Experience with F-18 and Ac-225 radiochemistry is advantageous.
A proven track record of initiating, leading, or significantly contributing to advanced research in chemistry or life sciences.
A mindset characterized by curiosity, creativity, collaboration, and openness to diverse thinking, along with a commitment to personal and professional development.
An interest in disruptive technologies and scientific trends, such as data science and automation, and their application to drug discovery.
The ability to work effectively in a fast-paced, team-oriented matrix environment.
Excellent oral and written communication skills along with strong influencing abilities.
Accessibility and Accommodation
Novartis is committed to supporting and providing reasonable accommodations to all individuals. If you require accommodations during the recruitment process due to a medical condition or disability, please reach out via email at Show e-mailm">, specifying the nature of your request along with your contact information. Be sure to include the job requisition number in your correspondence.
Why Novartis?
Helping individuals with diseases and their families requires more than innovative science. It takes a community of intelligent, passionate people like you—collaborating, supporting, and inspiring one another to achieve breakthroughs that change lives. Are you ready to join us in creating a brighter future together?
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Benefits and Rewards
Explore our handbook to discover how we will support you personally and professionally: Benefits & Rewards
How to Apply
Apply online using the form below. Please note that only applications matching the job profile will be considered.
Division
Biomedical Research
Business Unit
Pharma Research
Location
Switzerland
Site
Basel (City)
Company / Legal Entity
C028 (FCRS = CH028) Novartis Pharma AG
Functional Area
Research & Development
Job Type
Full time
Employment Type
Regular
Shift Work
No
Novartis is committed to creating an outstanding, inclusive work environment with diverse teams that reflect the patients and communities we serve.