Principal Scientist - Oncology Translational Research / Principal Scientistess - Oncology Translational Research

Job ID

REQ-10067104

Date: Apr 07, 2026

Location: Basel, Switzerland

Employment Type: Full time, onsite, #LI-Onsite

Summary

The Oncology Translational Research (OTR) group within Novartis Biomedical Research is seeking a highly motivated lab head to drive the translational strategy for early clinical radioligand therapy (RLT) programs. This role entails collaboration with various teams throughout the drug development process, including drug discovery, data science, and early clinical development groups. The successful candidate will lead a team and be responsible for designing and executing preclinical translational studies and clinical biomarker plans.

About the Role

The successful candidate will be responsible for:

• Leading a research team and collaborating with various groups across BR Oncology.
• Contributing to biomarker strategies and supervising translational experimental plans for various RLT drug discovery programs.
• Designing and conducting translational studies, elucidating the biological mechanisms driving response and resistance to RLT, and developing rational drug combinations.
• Mentoring and developing associates with varying levels of experience.

Essential Requirements

• Ph.D. in molecular, cellular, cancer biology, or related fields.
• A minimum of 2 years of postdoctoral and/or industry experience in a relevant Oncology/Cancer biology field.
• A recognized academic publication record.
• A deep understanding of cancer cell biology, along with familiarity with innovative cell and molecular biology techniques.
• Excellent creative thinking and problem-solving skills, coupled with scientific curiosity.
• Ability to work collaboratively and flexibly across various projects.
• Strong communication skills, with the ability to convey complex scientific concepts effectively.

Desirable Requirements

• Strong foundational knowledge and experience working on cell death mechanisms, as well as experience in DNA damage response and repair, radiobiology, or RLT.
• Expertise in prostate cancer biology.
• Proficiency in data mining and computational skills.
• A proven track record in managing a research team and scientific projects.

Accessibility and Accommodation

Novartis is committed to working with and providing reasonable accommodations to all individuals. If, due to a medical condition or disability, you need reasonable accommodation for any part of the recruitment process, or require more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com with your request and contact information. Kindly include the job requisition number in your message.

Why Novartis

Helping individuals affected by disease and their families goes beyond innovative science; it requires a community of passionate individuals like you. Collaborate, support, and inspire one another to achieve breakthroughs that change patients' lives. Are you ready to build a brighter future together?

For more information, visit: Novartis People and Culture

Benefits and Rewards

Discover the various ways we will help you thrive both personally and professionally. Refer to our handbook for more information.

Application Process

Apply online using the form below. Please note that only applications matching the job profile will be considered.

Division

Biomedical Research

Business Unit

Research

Location

Switzerland

Site

Basel (City)

Company / Legal Entity

C028 (FCRS = CH028) Novartis Pharma AG

Functional Area

Research & Development

Job Type

Full time

Employment Type

Regular

Shift Work

No

Principal Scientist - Oncology Translational Research