Principal Scientist - Oncology Translational Research / Principal Scientistess - Oncology Translational Research

Job ID

REQ-10067104

Apr 07, 2026

Switzerland

Summary

Location: Basel, Switzerland

Full time, onsite, #LI-Onsite

The Oncology Translational Research (OTR) group within Novartis Biomedical Research seeks a highly motivated lab head to drive the translational strategy for early clinical radioligand therapy (RLT) programs. This role involves collaborative work with various groups across the drug development spectrum, including drug discovery, data science, and early clinical development teams. The successful candidate will lead a team and be tasked with designing and executing preclinical translational studies and clinical biomarker plans.

About the Role

The Oncology Translational Research (OTR) group within Novartis Biomedical Research is looking for a dedicated lab head to spearhead the translational strategy for early clinical radioligand therapy (RLT) programs. This position will require collaboration with diverse teams throughout the drug development process, including those focused on drug discovery, data science, and early clinical development. The individual will be responsible for guiding a team in the design and execution of preclinical translational studies and clinical biomarker strategies.

Key Responsibilities

• Lead a research team and collaborate with groups across BR Oncology.
• Contribute to biomarker strategies and supervise translational experimental plans for various RLT drug discovery programs.
• Design and conduct translational studies, dissect the biological mechanisms driving response and resistance to RLT, and develop rational drug combinations.
• Mentor and develop associates with varying levels of experience.

Essential Requirements

• Ph.D. in molecular, cellular, cancer biology, or related fields.
• Minimum of 2 years of postdoctoral and/or industry experience in an oncology or cancer biology-related field.
• Recognized academic publication record.
• Deep understanding of cancer cell biology, with familiarity in innovative cell and molecular biology techniques.
• Excellent creative thinking and problem-solving skills, coupled with scientific curiosity.
• Proficiency in collaborative and flexible project management.
• Strong communication skills, adept at conveying complex scientific concepts.

Desirable Requirements

• Strong foundational knowledge and experience in cell death mechanisms, DNA damage response and repair, radiobiology, or RLT.
• Expertise in prostate cancer biology.
• Proficiency with data mining and computational abilities.
• Proven experience in managing research teams and scientific projects.

Accessibility and Accommodation

Novartis is committed to working with and providing reasonable accommodations to all individuals. If you require any accommodations due to a medical condition or disability during the recruitment process, please send an email to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Why Novartis

Helping individuals facing health challenges and their families requires more than innovative science; it demands a community of intelligent, passionate individuals like you. Together, we collaborate, support, and inspire one another, striving to achieve breakthroughs that transform patients' lives. Are you ready to create a brighter future together?

Learn more about us at https://www.novartis.com/about/strategy/people-and-culture.

Benefits and Rewards

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Division

Biomedical Research

Business Unit

Research

Location

Switzerland

Site

Basel (City)

Company / Legal Entity

C028 (FCRS = CH028) Novartis Pharma AG

Functional Area

Research & Development

Job Type

Full time

Employment Type

Regular

Shift Work

No

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