Principal Scientist - Oncology Translational Research / Principal Scientistess - Oncology Translational Research

Novartis Pharma AG - December 6, 2025

Job ID

REQ-10067104

Nov 20, 2025

Switzerland

Summary

Location: Basel, Switzerland
Full time, onsite, #LI-Onsite

The Oncology Translational Research (OTR) group within Novartis Biomedical Research is seeking a highly motivated lab head to drive the translational strategy for early clinical radioligand therapy (RLT) programs. This role involves collaborative work with various groups across the drug development spectrum, including drug discovery, data science, and early clinical development. The successful candidate will lead a team and be responsible for the design and execution of preclinical translational studies and clinical biomarker plans.

About the Role

The Oncology Translational Research (OTR) group within Novartis Biomedical Research is searching for a dynamic lab head to spearhead the translational strategy for early clinical radioligand therapy (RLT) programs. This role encompasses collaboration with various teams across the drug development continuum, including drug discovery, data science, and early clinical stages. The selected candidate will manage a research team and oversee the design and execution of pivotal preclinical translational studies and clinical biomarker plans.

Key Responsibilities

  • Lead a research team and collaborate with groups across BR Oncology.
  • Contribute to biomarker strategies and oversee translational experimental plans for various RLT drug discovery programs.
  • Design and conduct translational studies, investigating the biological mechanisms that drive response and resistance to RLT, as well as developing rational drug combinations.
  • Mentor and develop associates with varying levels of experience.

Essential Requirements

  • Ph.D. in molecular, cellular, cancer biology or related fields.
  • A minimum of 2 years of postdoctoral and/or industry experience in an oncology/cancer biology relevant field.
  • A recognized record of academic publications.
  • A deep understanding of cancer cell biology and familiarity with innovative cell and molecular biology techniques.
  • Excellent creative thinking and problem-solving skills, along with scientific curiosity.
  • Proficiency in collaborative and flexible work across various projects.
  • Strong communication skills, adept at conveying complex scientific concepts.

Desirable Requirements

  • Strong foundational knowledge and experience in cell death mechanisms, including expertise in DNA damage response and repair, radiobiology, or RLT.
  • Expertise in prostate cancer biology.
  • Proficiency in data mining and computational skills.
  • A track record in managing a research team and scientific projects.

Accessibility and Accommodation

Novartis is committed to providing reasonable accommodation to all individuals. Should you need assistance due to a medical condition or disability, please reach out via email to diversity.inclusion_ch@novartis.com, indicating the nature of your request and your contact information. Be sure to include the job requisition number in your message.

Why Novartis

At Novartis, we believe that helping people with disease and their families requires more than just innovative science; it requires a community of passionate individuals like you. Together, we can collaborate, support, and inspire one another to achieve breakthroughs that change patients' lives. Ready to create a brighter future together? Learn more about us.

Benefits and Rewards

Explore our handbook to discover the various ways we can support your personal and professional growth: Learn about our benefits.

Application Process

To apply, please use the form below. Only applications matching the job profile will be considered.

Company Information

Division: Biomedical Research
Business Unit: Research
Location: Switzerland
Site: Basel (City)
Company / Legal Entity: C028 (FCRS = CH028) Novartis Pharma AG
Functional Area: Research & Development
Job Type: Full time
Employment Type: Regular
Shift Work: No

Novartis is dedicated to fostering an outstanding, inclusive work environment with diverse teams that represent the patients and communities we serve.

Location : BASEL
Country : Switzerland

Application Form

Please enter your information in the following form and attach your resume (CV)

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