Postdoctoral Researcher / Postdoctoral Researcheress

Postdoc Position in Protocol Development for Isolation of Microbial Strains for Sustainable Protein Production

100%, Basel, fixed-term

We develop technologies to exploit whole-cell and enzyme catalysts for the manufacturing of substances utilized in sustainable chemistry, innovative food, and active pharmaceutical ingredients.

For a third-party funded project in the realm of innovative, non-agricultural food aimed at microbial protein manufacturing from reactive gases, we are offering a PostDoc position.

Project Background

This project is part of the EC-sponsored consortium HydroCow, which includes partners from the UK, Germany, and Finland, specializing in metabolic flux modeling, molecular engineering, manufacturing, and marketing.

In HydroCow, we are enhancing an earlier developed ultra-high-throughput screening platform that facilitates the rapid identification of improved industrial production strains. Central to this platform are microcolonies cultivated in gel capsules, which undergo fluorescence-based analysis for quantification of the product of interest. This technology will be utilized for recombinant protein secretion for the first time.

Job Description

The postdoctoral fellow will undertake the following tasks:

• Development of high-throughput assays, typically utilizing fluorescence mediated by biosensors or (bio)chemicals
• Characterization of assay performance using lead strains
• Execution of large-scale screening campaigns with up to 1E6 variant strains
• Co-representation and reporting of BPL results in consortium meetings
• Co-coordination of tasks with all consortium partners

Profile

• PhD in molecular biology, microbiology, or industrial biotechnology
• Strong communication skills (in English) and the ability to work collaboratively
• We are particularly interested in candidates with all or a subset of the following additional qualifications:
• A solid background in chemistry and spectrometric analyses
• Experience developing protocols from scratch (rather than using commercial kits)
• Ability to work under controlled atmospheres (e.g., glove boxes)
• Availability to commence employment promptly is advantageous

Workplace

The position will be based in a dynamic and innovative environment, promoting collaboration and intellectual growth.

We Offer

We provide:

• An intellectually challenging position within an inspiring interdisciplinary team
• Opportunities to engage in multifaceted, applied work in a larger international team that includes academia and industry
• Development of technologies and protocols with potential commercial applications
• Opportunities for personal development, including writing, presentation, and project management skills
• Possibilities to work with and supervise students
• Participation in international conferences and project workshops

We Value Diversity and Sustainability

In alignment with our values, ETH Zurich fosters an inclusive culture. We promote equality of opportunity, value diversity, and cultivate a work and learning environment that respects the rights and dignity of all staff and students. For more information, visit our Equal Opportunities and Diversity website. Sustainability is a core principle for us; we are committed to working towards a climate-neutral future.

Curious? So Are We.

We invite you to apply online using the form below. Please include the following documents:

• Letter detailing your background, interest, and motivation
• CV
• Certificates (transcripts for Master’s degree, certificate of doctoral degree)
• Two reference letters

For further information about BPL and D-BSSE, please visit our website. Questions regarding the position can be directed via email to Martin.Held@bsse.ethz.ch.

Please note that only applications matching the job profile will be considered.

About ETH Zurich

ETH Zurich is one of the world’s leading universities specializing in science and technology. We are renowned for our excellent education, cutting-edge fundamental research, and direct transfer of new knowledge to society. With over 30,000 individuals from more than 120 countries, our university promotes independent thought and an atmosphere that inspires excellence. Located in the heart of Europe, yet fostering connections worldwide, we work collaboratively to develop solutions to the global challenges of today and tomorrow.