Portfolio and Operations Change Manager / Portfolio and Operations Change Manageress

Portfolio and Operations Change Manager

Background

Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organizations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive significant impact. Seamless data sharing and access to models across gRED and pRED are essential for maximizing these opportunities.

The new Computational Sciences Center of Excellence (CS-CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist scientists in both pRED and gRED in delivering innovative and transformative medicines for patients worldwide. Within the CoE organization, the Portfolio & Operations team organizes and drives CoE core operations, portfolio strategy & management, administration, budget planning, vendor management, procurement interactions, and informatics operations, including managing cloud & software expenditures.

This team serves as both the strategic catalyst and operational backbone for the CoE, enabling business performance, transparency, and accountability. We are seeking an experienced Change Management Lead to drive the adoption and implementation of five top-priority operational initiatives. This role is critical in transitioning the CoE from fragmented, manual legacy processes to a unified, scalable "One Source of Truth" model.

The Perfect Candidate

We are looking for an experienced Change and Project Manager (Bachelor’s degree or higher; CCMP/Prosci or PMP/Agile preferred) with 3–5 years of experience in Healthcare Life Sciences. The ideal candidate will have a proven track record in large-scale transformation projects and be an exceptional communicator, capable of translating complex changes into clear, actionable messages. You should be a strategic thinker who independently develops ideas and drives operational execution, demonstrating agility and organization while managing multiple simultaneous workstreams. Fluency in English and readiness for international assignments are essential.

Tasks & Responsibilities

• CPL (Contracts, Procurement & Licensing): Transitioning to a centralized project intake tool and standardized contract workflows.
• TRU (Transparency of Resource Utilization): Implementing new CoE time reporting and financial WBS strategy.
• L&D (Compliance & Learning Management): Deploying a global CoE training matrix and automated system-based training.
• FinOps (Cloud Management): Establishing integrated cloud governance and unified financial frameworks.
• DOG (Deployment of Operational Guidelines): Launching a centralized "Policy Hub" for all CS CoE policies.
• Change Strategy & Planning: Create tailored change management roadmaps for each of the five initiatives, ensuring alignment with the broader P&O Operations vision.
• Communication Material Development: Design and produce high-impact communication materials, including executive read-outs, global announcements, and process Hub content.
• Stakeholder Coordination: Navigate complex stakeholder dynamics across the CS CoE and build consensus while ensuring regional readiness for global standards.
• Training & Adoption Support: Partner with the L&D and DOG leads to ensure end-user training and operational guidelines are effectively deployed and understood.
• KPI Tracking: Refine and track success metrics related to user adoption and process standardization to demonstrate measurable impact.

Must Haves

• Bachelor’s degree or higher; specialized certification in Change Management (e.g., CCMP, Prosci) or Project Management (PMP, Agile) is highly preferred.
• 3–5 years of experience in Healthcare Life Sciences (HCLS). Proven track record of managing change for large-scale operational transformations.
• Communication Specialist: Exceptional ability to translate complex operational changes into clear, actionable, and persuasive materials for diverse audiences.
• Strategic Execution: A strategic thinker who can move between high-level strategy and the tactical creation of change assets.
• Agility: Comfortable working in a dynamic environment and managing multiple, simultaneous workstreams with precision.
• Fluency in English is a must.

Reference Information

Reference Nr.: 924860SBI
Role: Portfolio and Operations Change Manager
Industry: Pharma
Workplace: Basel
Pensum: 80-100% (2 days remote, 3 days onsite)
Start: As soon as possible (Latest Start Date: 01.05.2026)
Duration: 12 months ++
Deadline: 09.04.2026

If you are interested in this position, apply online using the form below. Only applications matching the job profile will be considered.

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