100%, Basel, Fixed-Term
The Laboratory for Biological Engineering, led by Prof. Randall J. Platt at ETH Zurich in Basel, Switzerland, is at the forefront of developing genome engineering technologies. Our research spans a variety of fundamental and disease-focused domains. To further our mission, the Platt group is seeking a dedicated full-time (100%) PhD student to pioneer methods at the intersection of gene editing, functional genomics, protein engineering, and targeted protein degradation.
High-throughput perturbation technologies are essential for understanding protein function through the manipulation of DNA or RNA. However, methods for directly perturbing proteins, such as targeted protein degradation, have faced significant challenges in high-throughput applications. This project aims to create innovative technologies that integrate CRISPR-Cas and targeted protein degradation, facilitating high-throughput protein perturbation and prototype-to-phenotype mapping.
We are looking for a highly motivated and collaborative researcher to join our interdisciplinary team. The successful candidate will develop novel gene editing and targeted protein degradation methods, applying them to address fundamental biological questions and advancing induced proximity therapeutics.
The ideal candidate will possess a Master’s degree or equivalent in Molecular Biotechnology, Biochemistry, Molecular Medicine, Structural Biology, Molecular and Cellular Biology, or a related field. Experience in several of the following areas is preferred:
The candidate should be passionate about science and technology, and possess strong communication and collaboration skills in a highly interdisciplinary and international context. Proficiency in both oral and written English is essential, along with the ability to use scientific illustration tools such as Adobe Illustrator or similar software.
The position is based in the Department of Biosystems Science and Engineering (D-BSSE) at ETH Zurich in Basel, Switzerland. The D-BSSE is an interdisciplinary hub specializing in systems and synthetic biology, bioinformatics, data science, and engineering related to microfluidics and microfabrication. Our department is located within a vibrant biomedical research community with affiliations to leading academic institutions (e.g., Friedrich Miescher Institute, Biozentrum, and University of Basel) and major biotech and pharmaceutical companies (e.g., Novartis, Roche, Bayer, and Lonza). ETH Zurich is a global leader in science and technology, consistently ranked among the world's top universities. Basel is an international city near the borders of France and Germany, offering easy access to culture, nature, and opportunities for travel across Europe.
In alignment with our values, ETH Zurich fosters an inclusive culture. We promote equal opportunities, value diversity, and cultivate an environment where the rights and dignity of all staff and students are upheld. For more information, visit our Equal Opportunities and Diversity page to learn how we ensure a fair and supportive setting that allows everyone to thrive.
We look forward to receiving your online application, which should include the following documents:
Apply online using the form below. Only applications matching the job profile will be considered.
ETH Zurich is one of the world's leading universities specializing in science and technology. We are renowned for our excellent education, groundbreaking research, and the direct application of new knowledge in society. With over 30,000 individuals from more than 120 countries, our university promotes independent thinking in an inspiring environment that fosters excellence. Located in the heart of Europe, we connect globally to develop solutions for the challenges facing society today and in the future.
Location : Roche
Country : Switzerland