PhD Candidate in Neuromodulation and Arousal Regulation through Bio-/Neurofeedback

PhD Position in Neuromodulation and Arousal Regulation through Bio-/Neurofeedback

100%, Zurich, fixed-term

The newly established Brain-Body Regulation Lab at ETH Zurich (Department of Health Sciences and Technology) is dedicated to developing non-invasive self-regulation methods for modulating brain function during wake and sleep, while also exploring the interactions between the brain and other bodily functions. We primarily conduct studies with healthy volunteers, and future projects will include patient cohorts. We are currently seeking a motivated and skilled PhD student to join our team.

Project Background

This project investigates neuromodulatory systems, particularly the locus coeruleus, and their role in regulating brain arousal levels and their effects on bodily signals. Utilizing a novel biofeedback approach informed by eye pupil dynamics, along with neuroimaging, electrophysiological, and respiratory recordings, our aim is to understand and modulate these crucial brain functions and their impact on bodily physiology during wake and sleep.

Job Description

The successful candidate will design and conduct human experiments employing multimodal approaches to investigate the link between central and peripheral arousal levels during wake and sleep. A central focus of the project will involve using pupillometry, supplemented by other neurophysiological recordings, to indirectly assess activity within arousal-regulating brain systems and understand their role in supporting both brain and bodily functions through non-invasive interventions.

Your work will include:

• Development of study designs and research questions
• Configuration and integration of multimodal biosignal recording systems
• Hands-on data acquisition using non-invasive electrophysiological, respiratory, and pupillometry recordings during sleep and wake in humans
• Advanced signal processing
• Dissemination of research findings through scientific publications and presentations
• Supervision of (BSc and MSc) students

This project offers a unique opportunity to integrate and synchronize various physiological recordings, including EEG, ECG, respiratory recordings, and pupillometry. The successful candidate will participate in all aspects of scientific work, making this an exciting and challenging position.

Profile

We are seeking a candidate with the following qualifications:

• A Master's degree (or nearing completion) in health sciences and technology, neuroscience, psychology, neurophysiology, biomedical engineering, or a related field
• Programming experience (e.g., Matlab, Python)
• Experience with at least one electrophysiological recording method or other related experimental techniques
• The ability to design and conduct rigorous human experiments, particularly in synchronizing data from multiple sources
• Experience in setting up complex biosignal recordings is an advantage
• Strong communication skills, scientific curiosity, and a collaborative spirit
• Self-motivated, reliable, and organized
• Fluency in English; German language skills are an advantage

Workplace

You will be working in a vibrant and supportive environment that fosters scientific innovation and progress.

We Offer

A fully funded PhD position (approximately 4 years) in a stimulating scientific and social environment at a world-leading University. The project will integrate both lab work and computational analyses of gathered data, providing an excellent opportunity to establish a comprehensive portfolio of scientific work.

• Your work will have an impact: Join ETH Zurich, a place that not only supports your professional development but also actively contributes to positive societal change.
• We are committed to sustainability and maintaining a climate-neutral campus.
• Expect a variety of benefits, including public transport season tickets, car sharing, a wide range of sports activities offered by ASVZ, childcare, and attractive pension benefits.

We Value Diversity

In alignment with our values, ETH Zurich fosters an inclusive culture. We promote equal opportunities, value diversity, and cultivate a working and learning environment where the rights and dignity of all staff and students are upheld. Please visit our Equal Opportunities and Diversity website to learn more about our commitment to creating a fair and open environment that encourages growth and development.

Curious? So Are We!

Apply online using the form below. Your application should include the following documents:

• Curriculum Vitae detailing your educational history, awards, etc.
• Research motivation statement (maximum of two A4 pages) discussing your interests, goals, experiences, and how they align with the proposed research domain and activities
• Diplomas
• Names and email addresses of at least two references

Only applications matching the job profile will be considered.

Starting date: Summer 2025 (or upon mutual agreement).

For inquiries regarding this position, please contact Prof. Dr. Sarah Meissner at Show e-mail.ch">Show e-mail (no applications).

About ETH Zurich

ETH Zurich is a leading university specializing in science and technology, known for its excellent education, cutting-edge fundamental research, and its direct impact on society. With over 30,000 people from more than 120 countries, our university promotes independent thinking and an inspiring environment that cultivates excellence. Located in the heart of Europe, we forge connections globally to develop solutions for today's challenges and those of the future.