PhD Position - Biomedical Robotics in Hydrocephalus Research

100%, Zurich, fixed-term

The PhD position is part of an interdisciplinary research project at the intersection of robotics and biomedical engineering. This project is conducted in close collaboration with neurosurgeons from the University Hospital Zurich, biomedical engineers and veterinarians from the University of Zurich, as well as international collaborators from Umeå University in Sweden and the Massachusetts Institute of Technology in the US.

Hydrocephalus is a severe and common neurological disorder that occurs in various forms from childhood to old age. Our research primarily focuses on normal pressure hydrocephalus (NPH) in elderly patients, impacting approximately 6% of individuals over the age of 80. This disorder is characterized by an enlargement of brain ventricles, presumed to result from a mismatch in the secretion and resorption of cerebrospinal fluid (CSF). Patients often exhibit symptoms such as mental impairment and gait disturbance. Conventional treatment typically involves lifelong therapy with shunts that drain CSF from the brain ventricles into the abdomen, relying on passive mechanical pressure valves.

To enhance therapy for hydrocephalus patients, we integrate in silico and in vitro studies with animal experiments to gain a comprehensive understanding of the disorder and to develop intelligent mechatronic shunt systems.

Job description

The PhD position addresses the following goals:

• Developing mechatronic systems for in vivo applications (NPH animal model and active shunt)
• Designing and deploying advanced algorithms for estimation and control
• Conducting in vivo trials with sheep in collaboration with veterinary and clinical colleagues
• Signal analysis and data processing from acute and chronic in vivo trials
• Deriving dynamical system models for CSF simulation studies and hardware-in-the-loop shunt testing

Profile

Candidates should possess:

• A Master of Science degree from a recognized university (or nearing completion) in mechanical, electrical, robotics, control, or biomedical engineering
• A passion for practical and methodological work following a systematic approach in medical applications
• Strong interest in a highly interdisciplinary environment
• A background in hardware development, control theory, signal processing, and machine learning
• Curiosity, open-mindedness, and effective communication skills
• Proficient oral and written English skills

Workplace

Join us at ETH Zurich, where your work contributes to making a significant impact in society. We are committed to a sustainable and climate-neutral campus and offer numerous benefits, such as public transportation discounts, car sharing, a wide range of sports activities through ASVZ, childcare services, and attractive pension plans.

We value diversity

In alignment with our values, ETH Zurich promotes an inclusive culture. We advocate for equal opportunity, value diversity, and nurture a working environment where the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to learn how we maintain a fair and open environment that allows everyone to grow and thrive.

Curious? So are we.

Apply online using the form below. Please ensure your application includes the following documents:

• CV
• A short statement of objectives and research interests (1-2 pages)
• Transcripts of all degrees obtained (in English)
• Names and contact information of three references
• One publication (e.g., thesis or paper)

Please note that only applications matching the job profile will be considered. For further information about the Department of Mechanical and Process Engineering/Intelligent Control Systems, visit our website. Questions regarding the position can be directed to Dr. Marianne Schmid Daners at Show e-mail (no applications).

About ETH Zürich

ETH Zurich is one of the world's leading universities specializing in science and technology. We are renowned for our exceptional education, pioneering research, and the direct transfer of new knowledge into society. With over 30,000 individuals from more than 120 countries, our university fosters independent thought and an environment that inspires excellence. Positioned in the heart of Europe yet connected globally, we collaborate to develop solutions for today's and tomorrow's challenges.