Molecular Cell Biology Research Assistant / Associate, Maternity Cover (100%) - Ref.: IOB168
The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is seeking a highly motivated Research Assistant or Research Associate to join the Retinal Organoid Platform, covering for a team member on maternity leave from July 2026 to January 2027. IOB is a pioneering research institute that merges basic and clinical research, dedicated to driving innovations in understanding vision and its associated diseases while developing new therapies for vision loss. Here, your expertise will be valued, your abilities challenged, and your knowledge expanded.
The Human Organoid Platform employs human retinal organoids coupled with genome engineering techniques to create disease models and evaluate novel gene-therapy approaches for human blinding disorders. Our platform is continuously innovating methodologies to enhance the culture and analysis of retinal organoids and is dedicated to implementing new read-outs for ocular disease phenotypes within these organoids.
Your Responsibilities
- In vitro culture of human pluripotent stem cells and retinal organoids.
- Genome engineering of pluripotent stem cells using CRISPR/Cas9, along with characterization of mutant iPSCs and organoids.
- Vector construction and molecular cloning.
- Analysis of retinal organoids through various histology and microscopy techniques.
- Application and enhancement of new methodologies to improve organoid culture and analysis.
- Participation in figure and paper preparation.
- Contribution to lab management and organization.
- Close collaboration with team members and other IOB groups.
Requirements
- Master’s or PhD degree (or equivalent) in molecular biology or a related field.
- Excellent aseptic cell culture techniques.
- Experience with confocal microscopy and image analysis workflows.
- Independence in planning, conducting, analyzing, and troubleshooting molecular biology and cell culture experiments.
- Willingness to work with lentivirus, human tissue, and standard hazardous laboratory compounds.
- Enthusiasm for establishing and optimizing new protocols and techniques.
- Highly organized, detail-oriented, and proficient with computer applications.
- Strong written and verbal communication skills.
- Availability to work some weekends and public holidays.
- Fluency in both oral and written English.
We Offer
- Scientific Excellence & Impact: Join a highly motivated research institute at the forefront of vision research, supported by state-of-the-art facilities in an international, cutting-edge research environment in Basel.
- An Environment Built for Performance: We provide conditions that enable you to perform your best work with a commitment to supporting long-term excellence and family-friendly policies.
- Practical Support & Accessibility: Our convenient Basel location features excellent public transport, subsidized meals, childcare support, and access to university sports facilities (Unisport).
- A Culture of Mutual Trust: We seek colleagues who contribute motivation, innovation, and dedication; in return, we offer the resources, flexibility, and environment in which exceptional work thrives.
Apply online using the form below. Note that only applications matching the job profile will be considered.