Medical Scientist / Medical Scientistess

Job Opportunity: Principal Scientist in Immunology

Are you a highly accomplished Immunologist with a proven track record of leading scientific teams and driving biologics discovery programs in autoimmune and inflammatory diseases? Proclinical is proud to announce an opening for a Principal Scientist position, where you will oversee groundbreaking work in inflammation and immunology. You’ll play a central role in shaping therapeutic approaches, developing next-generation biologic therapies, mentoring talented scientists, and advancing programs from target identification to preclinical development.

As a leader at the forefront of immunology research, you will support multidisciplinary programs spanning target identification, pharmacology, translational research, and therapeutic antibody development. You will leverage your hands-on scientific expertise and leadership skills to advance novel biologic therapies from early discovery to preclinical development.

Responsibilities

• Lead and mentor a team of laboratory-based scientists, supporting scientific delivery and career development.
• Design, oversee, and interpret complex in vitro and in vivo pharmacology studies.
• Drive the development of novel therapeutic strategies within autoimmune and inflammatory disease programs.
• Design and optimize immune-based assays to support target validation and antibody discovery.
• Collaborate closely with experts across immunology, translational medicine, protein engineering, biomarkers, and clinical development.
• Work with CRO partners to coordinate efficacy and pharmacology studies.
• Develop and implement endpoint and mechanism-of-action studies, including ex vivo immune profiling.
• Identify project risks, influence program strategy, and support key decision-making discussions.
• Contribute to scientific publications, patents, regulatory documentation, and due diligence activities.
• Represent research programs through conference presentations and external scientific collaborations.

Key Skills and Requirements

• PhD in Immunology, Life Sciences, or a related discipline.
• Minimum 5 years' experience in immunology, inflammation research, or biologics drug discovery.
• Strong understanding of autoimmune disease biology and immune system mechanisms.
• Proven experience leading scientific projects and mentoring research teams.
• Expertise in in vitro pharmacology, assay development, and immune profiling.
• Experience supporting biologics, antibody, or therapeutic development programs.
• Strong publication record with peer-reviewed scientific contributions.
• Excellent communication, stakeholder management, and leadership skills.
• Experience in the biotechnology or pharmaceutical industry.
• In vivo pharmacology program leadership.
• Translational research and target validation experience.
• Experience working with CROs and external research partners.
• Contributions to IND-enabling studies, patent applications, or due diligence activities.
• Exposure to strategic portfolio or pipeline decision-making.

If you are interested in this exciting opportunity, please apply online using the form below. Only applications matching the job profile will be considered.

Proclinical is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. Proclinical is acting as an Employment Agency in relation to this vacancy.