Lead Mechatronics Engineer / Lead Mechatronics Engineeress

ETH Zurich - February 16, 2026

Lead Mechatronics Engineer: Next-Generation Live-Cell AFM Nano-Imaging

80%, Zurich, fixed-term

The Laboratory of Molecular Medicine, led by Prof. Yohei Yamauchi, is developing the ViViD-AFM V2.0—a next-generation nano-imaging system. This project focuses on transitioning from academic prototypes to commercial-grade industrial systems while ensuring complete IP independence from legacy V1.0 patents.

Project Background

The Laboratory of Molecular Medicine, under the direction of Prof. Yohei Yamauchi, is entering a transformative phase of the ViViD-AFM (Virus-View Dual Confocal and Atomic Force Microscopy) project. We are seeking a visionary Lead Mechatronics Engineer to drive the design and development of the V2.0 system in collaboration with the Lead Architect. This role is strategically important as it focuses on the physical realization of a next-generation high-speed AFM system tailored for biological research.

Job Description

The Lead Mechatronics Engineer will be responsible for the physical realization and hardware integration of the V2.0 system. This position represents a Critical Tandem Hire, where your success is closely linked to the architectural framework being developed concurrently by the Lead Architect.

Profile

  • Hardware Realization: Translate abstract architectural requirements into functional ViViD-AFM V2.0 mechatronic hardware.
  • Precision Engineering: Design and implement sub-nanometer control systems and high-precision scanning devices.
  • Specialized Mechatronics: Substantial track record in the physical realization of high-speed AFM hardware specifically for soft cell surfaces.
  • Control Systems: Expert-level knowledge of sub-nanometer control systems, exceeding the scope of generic mechatronics.
  • Collaborative Design: Proven ability to work closely with architects to solve complex system integration challenges.
  • Academic/Industrial Background: Experience in high-precision scanning mechanisms and a history of transitioning research to industry.
  • Technical Synchronization: Work in immediate technical alignment with the Lead Architect to ensure seamless hardware-software-architecture integration.
  • Prototyping: Oversee the transition from early-stage hardware components to a commercial-grade integrated device.

Workplace

The position offers a unique bridge between high-level academic research at ETH Zurich and the dynamic environment of a high-tech startup. You will have the opportunity to lead the architectural development of a system that aims to redefine nano-imaging. We promote a highly collaborative atmosphere and will assist in your transition into the spin-off phase.

We Value Diversity and Sustainability

In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity, and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Sustainability is a core value for us - we are consistently working towards a climate-neutral future.

Curious? So Are We.

We look forward to receiving your online application using the form below. Please include the following documents:

  • Cover Letter
  • Curriculum Vitae (Must detail extensive leadership experience in precision instrumentation architecture or high-speed AFM hardware.)
  • List of Publications and Patents

Further information about ETH Zurich and the Yamauchi Lab can be found on our website.

Questions regarding the position should be directed to Prof. Yohei Yamauchi at yohei.yamauchi@pharma.ethz.ch (no applications).

Please note that only applications matching the job profile will be considered.

About ETH Zurich

ETH Zurich is one of the world’s leading universities specializing in science and technology. We are renowned for our excellent education, cutting-edge fundamental research, and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for today's and tomorrow's global challenges.

Location : Zürich
Country : Switzerland

Application Form

Please enter your information in the following form and attach your resume (CV)

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