Lead Architect / Lead Architectess

Lead Architect: Next-Generation Live-Cell AFM Nano-Imaging

80%, Zurich, fixed-term

The Laboratory of Molecular Medicine, led by Prof. Yohei Yamauchi, is developing the ViViD-AFM V2.0—a next-generation nano-imaging system. This project aims to transition from academic prototypes to commercial-grade industrial systems while ensuring complete IP independence from legacy V1.0 patents.

Project Background

The Laboratory of Molecular Medicine is embarking on a transformative phase of the ViViD-AFM (Virus-View Dual Confocal and Atomic Force Microscopy) project. We are seeking a visionary Lead Architect to drive the design and development of the V2.0 system. This role is critical for establishing technical novelty, securing a new IP portfolio, and preparing for our upcoming spin-off transition.

Job Description

As the Lead Architect, you will have significant technical autonomy over the system's design and technical roadmap. You will lead the effort to translate complex research requirements into a scalable, novel architecture that avoids infringement of existing patents while maintaining high-speed performance for live-cell imaging.

Profile

• System Architecture & Roadmap: Define the technical vision and high-level design for ViViD-AFM V2.0, ensuring a scalable and robust system architecture.
• IP Strategy & Novelty Design: Drive the design process to ensure technical independence from previous versions, establishing a fresh patent portfolio for V2.0.
• Technical Coordination: Collaborate closely with the Lead Mechatronics Engineer to align hardware development with system-wide architectural goals.
• Specialized Expertise: Possess deep knowledge of high-speed AFM hardware dedicated to soft cell surface imaging.
• Experience: Proven ability to transition from early-stage academic prototypes to industrial commercial-grade systems.
• IP Knowledge: Analyze legacy systems and design innovative, IP-independent technical frameworks.
• Education: Degree in Physics or Engineering with a specialization in precision instrumentation.

Workplace

You will bridge high-level academic research at ETH Zurich and the dynamic environment of a high-tech startup. You will have the opportunity to lead the architectural development of a system that will redefine video-rate nano-imaging. We promote a highly collaborative atmosphere and will support your transition into the spin-off phase. ETH Zurich also assists with permit processes (e.g., B-Permit sponsorship) for international candidates.

We Value Diversity and Sustainability

In alignment with our core values, ETH Zurich fosters an inclusive culture, promoting equality of opportunity and nurturing a working environment that respects the rights and dignity of all staff and students. Visit our Equal Opportunities and Diversity website to learn how we create a fair and open environment that allows everyone to thrive. Sustainability is also integral to our mission, and we continuously strive towards a climate-neutral future.

Curious? So Are We.

Apply online using the form below. Please ensure you include the following documents:

• Cover Letter
• Curriculum Vitae (Must detail extensive leadership experience in precision instrumentation architecture or high-speed AFM hardware.)
• List of Publications and Patents

For further information about ETH Zurich and the Yamauchi Lab, please visit our website. Questions regarding the position should be directed to Prof. Yohei Yamauchi at yohei.yamauchi@pharma.ethz.ch (please do not send applications via email).

Only applications matching the job profile will be considered.

About ETH Zurich

ETH Zurich is one of the world's leading universities specializing in science and technology. We are renowned for our excellent education, cutting-edge research, and the direct transfer of knowledge into society. Over 30,000 people from more than 120 countries consider our university a place that fosters independent thinking and inspires excellence. Located in the heart of Europe while connecting globally, we collaborate to develop solutions for the challenges of today and tomorrow.