Join the NEXUS Personalized Health Team
The ETH Zurich technology platform NEXUS Personalized Health empowers discovery and translational research focused on personalized health. We offer a diverse range of expertise across Clinical Bioinformatics, Biostatistics, Software Engineering, Systems Operations, and Screening & Lab Automation.
Within this vibrant, multidisciplinary environment, the Clinical Bioinformatics group bridges computational biology and clinically applicable outcomes, actively working between biomedical research and clinical practice. Our initiatives include project-specific analyses, the integration of high-dimensional molecular data, and the development of robust analysis workflows in collaboration with academic institutions and hospitals.
Position: Group Leader Clinical Bioinformatics
As the Group Leader of Clinical Bioinformatics, you will manage a team of bioinformatics analysts and software engineers, ensuring that all analyses and workflows are reproducible, scalable, and suitable for translational and clinical contexts. Your role involves driving innovation through continuous evaluation of emerging technologies and analytical methodologies, integrating cutting-edge methods into clinical research. An essential aspect of your job will be to strategically manage clinical and translational projects by engaging actively with stakeholders.
Key Responsibilities
- Project Management: Structure and oversee projects from start to finish, defining scope, planning milestones, managing risks, and maintaining documentation according to translational and clinical quality standards.
- Technical Leadership: Lead the development and enhancement of pipelines using Nextflow and Snakemake while establishing standards for workflow engineering, testing, documentation, and long-term maintainability.
- Delivery Ownership: Ensure timelines, quality, and stakeholder alignment are met across multiple projects of varying scopes.
- Project Acquisition and Customer Management: Cultivate relationships with researchers, clinicians, and partners while translating their needs into clear deliverables and expectations.
- Clinical Reporting and Decision Support: Convert complex, multimodal, and large-scale results into clear outputs for physicians, such as dashboards and web-based reporting tools.
- Clinician Partnership: Understand clinician needs, streamline the interface, and allow your team to manage the technical complexities.
- Innovation and Scientific Advancement: Stay updated on developments in bioinformatics, AI, and data-driven medicine, evaluating and translating promising approaches into clinically applicable solutions.
- Cross-Team Collaboration: Collaborate closely with Software Engineering, Systems Operations, Biostatistics, and Screening & Lab Automation teams to deliver integrated solutions.
- People Leadership: Recruit, mentor, and develop team members, fostering knowledge exchange and high performance standards.
- Resource Management: Plan team capacity, prioritize tasks, and contribute to group budgeting and reporting.
Self-Assessment: Ideal Candidate
In this role, you will excel if you:
- Enjoy managing projects from inception to delivery, collaborating closely with clinicians and partners.
- Prefer interdisciplinary work and building strong relationships rather than operating in isolation.
- Are comfortable leading teams, setting priorities, and being accountable for results.
- Thrive on developing dependable workflows and continuously enhancing their reproducibility and scalability.
- Can distill complex data into user-friendly decision-support outputs that meet physicians' needs.
- Set high standards for workflow engineering and documentation, and enjoy leading your team to meet these expectations.
Essential Qualifications
- Proven leadership experience in clinical bioinformatics, genomics, or translational research.
- Hands-on experience in developing and refining analysis pipelines and reusable components.
- Proficient in workflow management tools such as Nextflow and/or Snakemake.
- Daily use of Git version control is a must.
- Strong communication skills with clinicians and stakeholders in English.
Highly Desired Qualifications
- Solid programming skills in Python or R with strong code quality practices.
- Experience with genomic/transcriptomic quality control and reporting.
- A background across various data types, including variant calling and single-cell sequencing analysis.
Advantageous Skills
- Experience in statistics or software engineering practices beyond basic scripting.
- Familiarity with HPC usage and Bash.
- Knowledge of German is a plus.
At NEXUS, we cherish knowledge exchange and teamwork, valuing each individual’s unique expertise. We have a flat organizational structure and a proactive attitude, offering flexible working hours, family-friendly models, training opportunities, and an exciting field of work at the forefront of translational research.
To explore this opportunity further, apply online using the form below. Please note that only applications matching the job profile will be considered.
For additional information about NEXUS Personalized Health, please visit our website. For questions regarding the position, contact Dr. Daniel Stekhoven at stekhoven@nexus.ethz.ch or Dr. Franziska Singer at singer@nexus.ethz.ch.