Join NEXUS Personalized Health
The ETH Zurich technology platform NEXUS Personalized Health empowers discovery and translational research geared toward personalized health. We provide a diverse range of expertise across Clinical Bioinformatics, Biostatistics, Software Engineering, Systems Operations, and Screening & Lab Automation.
Situated within this multi-disciplinary environment, the Clinical Bioinformatics group is dedicated to translating computational biology into clinically viable outcomes. Our work includes project-tailored analyses and the integration of high-dimensional molecular data, encompassing whole-genome variant calling, decision support, and single-cell sequencing analysis. We collaborate closely with academic institutions and hospitals to develop and expand robust analysis workflows and reusable components.
Position: Group Leader Clinical Bioinformatics
As the Group Leader in Clinical Bioinformatics, you will lead a team of bioinformatics analysts and software engineers. Your role will ensure that analyses and workflows are reproducible, scalable, and suitable for translational and clinical contexts. You will drive innovation by continuously assessing emerging technologies and analytical approaches, incorporating cutting-edge methods into clinical and translational research. A critical aspect of your role will be to secure, prioritize, and strategically manage clinical and translational projects through active stakeholder engagement.
Key Responsibilities
- Project Management: Structure and oversee projects end-to-end, ensuring clear scope definition, milestone planning, risk management, documentation standards, and processes aligned with translational and clinical quality requirements.
- Technical Leadership: Drive the development and extension of pipelines using Nextflow and Snakemake. Set high standards for workflow engineering, testing, documentation, and long-term maintainability.
- Delivery Ownership: Assume responsibility for timelines, quality, and stakeholder alignment across multiple projects with varying scopes.
- Project Acquisition and Customer Management: Build relationships with researchers, clinicians, and partners, shape projects, and translate needs into clear deliverables and expectations.
- Clinical Reporting and Decision Support: Convert complex, multimodal, and large-scale results into coherent outputs for physicians, including dashboards and web-based reporting.
- Clinician Partnership: Listen attentively, clarify what is useful, and maintain simplicity in the interface while your team manages technical complexities.
- Innovation and Scientific Advancement: Stay at the forefront of developments in bioinformatics, AI, and data-driven medicine, evaluating emerging methods and technologies and translating promising approaches into robust, clinically applicable solutions.
- Cross-Team Collaboration: Work closely with Software Engineering, Systems Operations, Biostatistics, and Screening & Lab Automation groups to deliver integrated solutions end-to-end.
- People Leadership: Recruit, mentor, and develop team members, fostering knowledge exchange and maintaining high standards.
- Resource Management: Plan capacity, prioritize work, and contribute to budgeting and reporting for the group.
Self-Assessment: You Will Thrive If...
- You enjoy owning projects from initial discussions with clinicians and partners to delivering robust, reusable solutions with clear outcomes.
- You value interdisciplinary collaboration and building strong partnerships with clinicians and cross-functional teams.
- You are comfortable setting direction, making prioritization decisions, and being accountable for timelines and quality.
- You take pride in developing workflows that others rely on and strive for continuous improvement in reproducibility, scalability, and impact.
- You are adept at transforming complex, multimodal data into clear decision-support outputs tailored to physician needs.
- You uphold high standards for workflow engineering, testing, and documentation, and enjoy guiding a team to meet those standards collectively.
Qualifications
- Non-Negotiables:
- Proven leadership experience in clinical bioinformatics, genomics, or translational research delivery.
- Hands-on experience developing and extending analysis pipelines and reusable components.
- Workflow management proficiency with Nextflow and/or Snakemake, along with the ability to set team standards.
- Regular practice with Git version control is essential.
- Strong communication skills with clinicians and adept in stakeholder management.
- Excellent proficiency in English.
- Strongly Expected:
- Solid programming skills in Python or R, with a strong emphasis on code quality (reviews, testing, and documentation).
- A proven track record across diverse data types, including variant calling, expression analyses, and single-cell sequencing analysis.
- Experience with quality control and reporting in genomics/transcriptomics.
- Advantageous:
- Experience in statistics or software engineering practices beyond scripting.
- Familiarity with HPC usage and Bash.
- Knowledge of German.
Why Join Us?
At NEXUS, we value knowledge exchange and teamwork, where each member contributes their unique expertise. Our flat hierarchies foster a can-do attitude, and we offer flexible working hours, family-friendly models, training opportunities, and a dynamic work environment at the forefront of translational research.
Apply online using the form below. Please ensure your application matches the job profile, as only applications matching the criteria will be considered.