Job ID
REQ-10079939
Date
June 08, 2026
Location
Basel, Switzerland #onsite
Summary
We are looking for a collaborative and scientifically strong professional to lead formulation project initiatives and biopharmaceutic expertise across innovative oral drug product development programs. In this role, you will oversee formulation and manufacturing activities for small-molecule oral dosage forms, enhancing the understanding of how molecular properties, formulation design, and process parameters impact absorption, bioavailability, and in vivo performance. You will collaborate across TRD, PHAD, PK Sciences, Translational Medicine, and development sub-teams to shape integrated, data-driven strategies that support development from first-in-human studies to scale-up, transfer, and regulatory submission.
About the Role
Key Responsibilities
- Lead formulation development and manufacturing process activities for oral dosage forms, from early clinical phases through final formulation and process definition, for Phase 3 and beyond.
- Develop and maintain integrated project plans that align formulation, control strategy, biopharmaceutic assessments, bridging strategies, and supply activities with overall program objectives.
- Provide scientific insight into the relationship between drug substance properties, dosage form design, dissolution, permeability, absorption, and in vivo performance.
- Design, interpret, and integrate in vitro, in silico, and in vivo biopharmaceutic studies to support formulation selection and development decisions.
- Collaborate as a key partner within cross-functional drug product sub-teams, closely coordinating with Pharmaceutical Development, Chemistry & Analytical Development, PK Sciences, Translational Medicine, and technical operations.
- Contribute to scientific documentation and support CMC and development dossiers, including responses to health authority questions and regulatory inspections.
- Employ innovative approaches such as predictive modeling, biorelevant testing, quality-by-design principles, and digital methods in formulation and biopharmaceutic development.
- Share knowledge, support colleagues, and enhance scientific capabilities across teams.
What You’ll Bring
- Advanced degree in Pharmaceutical Sciences, Pharmaceutical Technology, Chemical Engineering, Chemistry, or a related scientific field; a PhD or equivalent experience is valued.
- Relevant industry experience in formulation development and/or biopharmaceutics within pharmaceutical development, particularly for small-molecule oral dosage forms.
- Broad understanding of formulation design, manufacturing process development, absorption science, and performance-based drug product development.
- Knowledge and experience with amorphous drug product manufacturing processes, formulation design, and stability evaluation.
- Experience with technical approaches such as predictive modeling, dissolution and permeability studies, advanced DoE designs, and experimental strategies that support biopharmaceutic understanding, formulation, and process development.
- Familiarity with CMC documentation and GxP environments, including GMP and GLP expectations.
- Proven ability to work across functions, solve scientific problems, communicate clearly, and contribute to multidisciplinary teams.
- Strong scientific writing, presentation, collaboration, and mentoring skills are an advantage.
Commitment to Diversity and Inclusion
Novartis is dedicated to creating an outstanding, inclusive work environment with diverse teams that reflect the patients and communities we serve.
Accessibility and Accommodation
Novartis is committed to ensuring reasonable accommodations for all individuals. If you require accommodations due to a medical condition or disability, please reach out via email to inclusion.switzerland@novartis.com, including the nature of your request and your contact information. Please mention the job requisition number in your message.
Why Novartis
Helping people facing disease and their families takes more than innovative science. It requires a community of smart, passionate individuals like you working together to achieve breakthroughs that change patients' lives. Ready to create a brighter future together? Learn more.
Benefits and Rewards
Discover all the ways we can support your personal and professional growth. Read our handbook.
Division
Development
Business Unit
Development
Location
Switzerland
Site
Basel (City)
Company / Legal Entity
C028 (FCRS = CH028) Novartis Pharma AG
Functional Area
Research & Development
Job Type
Full time
Employment Type
Regular
Shift Work
No
Formulation Project Leader (Early Phase)
Apply online using the form below. Only applications matching the job profile will be considered.