Bioinformatics Scientist / Bioinformatics Scientistess

Job Opportunity: Bioinformatics Scientist

The Laboratory for Biological Engineering, led by Prof. Randall J. Platt at ETH Zurich in Basel, Switzerland, is at the forefront of developing technologies at the intersection of biological engineering, molecular perturbation technologies, and functional genomics. Our mission is to advance research that contributes to understanding and treating diseases.

Position Overview

We are seeking a skilled Bioinformatics Scientist to collaborate closely with Professor Platt, guiding the group’s computational research, contributing to ongoing projects, and exploring independent research avenues that align with the laboratory’s objectives.

Key Areas of Contribution

• In Vivo Single-Cell CRISPR Perturbation Screens: Engage in innovative CRISPR perturbation screens to unravel gene function at scale, and help develop pipelines for large-scale datasets.
• Transcriptome Recording and Cellular History Reconstruction: Advance our CRISPR-based transcriptional recording methods to encapsulate transient cellular events and develop analytics for complex biological environments.

Responsibilities

The successful candidate will:

• Collaborate with laboratory members to plan experiments and develop computational methods.
• Analyze multi-omic datasets, including transcriptomics, metagenomics, metabolomics, and proteomics.
• Publish research findings, engage in grant writing, and contribute to academic collaborations and partnerships.
• Provide mentorship and supervision to trainees and help foster a collaborative work environment.

The distribution of time for responsibilities will typically be: research (70%), supervision of trainees (20%), and service (10%).

This position is anticipated to be filled at the Established Researcher (Oberassistent) level, with opportunities for career advancement and professional development through a structured plan with defined milestones.

Qualifications

The ideal candidate will possess:

• A PhD or equivalent in bioinformatics, computational biology, or a related field, along with substantial postdoctoral experience (greater than 6 years).
• Expertise in bioinformatics methods and computational biology.
• A proven record of software development, including the creation of computational tools for the research community.
• Strong leadership and mentorship abilities to guide trainees effectively.
• Excellent communication skills, with the ability to present complex concepts to both technical and non-technical audiences.
• A history of impactful publications and successful grant writing.

Location and Environment

This position is based in the Department of Biosystems Science and Engineering (D-BSSE) at ETH Zurich, which is known for its interdisciplinary approach to systems biology, bioinformatics, and engineering sciences. The department benefits from its proximity to a vibrant biomedical research hub and collaborations with premier academic institutions and prominent biotech and pharmaceutical companies.

Application Process

We invite you to apply online using the form below. Only applications matching the job profile will be considered.

Documents required for your application include:

• A cover letter detailing your scientific background, skills, and motivation to join our group.
• An updated CV.
• Your diplomas and course transcripts.
• Contact information for at least two referees.

Important Dates

Initial Zoom interviews will be conducted on 1 or 2 April 2026, followed by in-person interviews on 16 or 17 April 2026. We expect the ideal start date for this role to be 1 August 2026.

For further inquiries, please contact Prof. Platt. We look forward to receiving your application!