Bioinformatics Scientist / Bioinformatics Scientistess

Bioinformatics Scientist / Data Scientist

100%, Zurich, fixed-term

The Musculoskeletal Bioengineering Laboratory, led by Prof. Dr. Tristan März, is an interdisciplinary research group dedicated to understanding the pathophysiology of arthritis. Our work combines in vitro models with diverse cell types and in vivo models of joint injury and inflammatory arthritis to uncover inflammation and fibrosis-related mechanisms that contribute to joint disease. Our ultimate goal is to identify and target novel molecular mechanisms that underlie inflammation and tissue degeneration, paving the way for innovative disease-modifying therapies.

Project Background

We are seeking a highly motivated Bioinformatics Scientist / Data Scientist to engage in multi-omics data analysis. This individual will play a pivotal role in analyzing high-dimensional biological datasets, developing and maintaining bioinformatics pipelines, and collaborating closely with experimental scientists to translate computational findings into biological insights. This position is ideal for candidates ranging from M.S.-level scientists with relevant experience to early- to mid-career Ph.D.-trained researchers seeking an independent and impactful role in an academic research environment.

Job Description

• Lead and support multi-omics data analysis across in vitro, in vivo, and clinical datasets
• Maintain, improve, and develop reproducible bioinformatics pipelines
• Integrate computational analyses with experimental and clinical data to generate biologically meaningful insights
• Stay up-to-date with emerging computational methods and apply them to ongoing research questions
• Communicate results effectively within the lab and to a broader scientific audience

Profile

Education & Experience:

• Master's degree required; Ph.D. preferred in Computational Biology, Bioinformatics, Data Science, Computer Science, Informatics, or a closely related field
• Master's degree with 3+ years of relevant research or industry experience, or
• Ph.D. with 0+ years of postdoctoral or equivalent experience

Technical Expertise:

• Proficiency in R and Python (MATLAB experience is a plus)
• Ability to analyze high-dimensional bioinformatics datasets, including multi-omics data (e.g., transcriptomics, epigenomics, proteomics, spatial, or single-cell data) using existing pipelines
• Demonstrated ability to enhance, optimize, and extend existing computational pipelines, as well as design and implement new workflows
• Experience working with large and complex datasets
• Strong ability to read, interpret, and implement methods from current bioinformatics and computational biology literature
• Experience using and maintaining GitHub repositories for version control and collaborative development
• Familiarity with conda environments, Jupyter notebooks, and R Markdown for reproducible research

Domain Knowledge:

• A background or strong interest in genomics, musculoskeletal biology, inflammation, tissue degeneration, or related biological systems is highly desirable

Preferred Skills & Attributes:

• Strong organizational skills, including time management and attention to detail
• Excellent problem-solving and analytical abilities
• Strong written and verbal communication skills
• Ability to present computational methods and biological results clearly to audiences with varying levels of expertise
• Interest in interdisciplinary collaboration with experimental biologists, clinicians, and engineers
• Demonstrated ability to provide technical leadership or mentorship is a plus

Workplace

ETH Zurich offers a friendly and collaborative environment. You will be part of a dedicated team engaged in innovative research within an international and academic setting.

We Offer

• A friendly, dedicated, and supportive team
• A varied role in an international academic environment
• Flexible working hours and attractive employment conditions
• Opportunities for personal and professional development

We Value Diversity and Sustainability

In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity, and nurture a working and learning environment where the rights and dignity of all our staff and students are respected. Sustainability is a core value for us as we consistently work towards a climate-neutral future.

Curious? So Are We!

We look forward to receiving your application. Please apply online using the form below.

Only applications matching the job profile will be considered.

Further information about the Musculoskeletal Bioengineering Lab can be found on our website. Questions regarding the position should be directed to Ms. Aanya Mohan at aanya.mohan@hest.ethz.ch (no applications).

About ETH Zürich

ETH Zurich is one of the world’s leading universities specializing in science and technology. We are renowned for our excellent education, cutting-edge fundamental research, and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a hub for independent thinking and an environment that inspires excellence. Located in the heart of Europe yet forging connections across the globe, we work collaboratively to develop solutions for the global challenges of today and tomorrow.